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Summary

A highly competent, motivated, and enthusiastic administrative medical and research intern with experience of working as part of a team in several major scientific projects. Proficiency in both written and spoken English. A solid grasp of basic cell culture and animal experimentation skills in rats and mice. Proficiency in bioinformatics analysis and scientific illustration. Approachable, well presented and able to establish good working relationships with a range of different people. Possessing a proven ability to generate innovative ideas and solutions to problems. Great cellular and molecular immunology. Currently looking for a suitable position in a lab in the realm of stem cell research with a immunology perspective.

Residence

Shanghai

Birthdate

2001-11-09

Graduation Year

2025.6 Shanghai University of Traditional Chinese Medicine

Gender

Male/He/Him

Work Experience

Collaboration with Huashan Hospital in EBV Research

Research Intern

January 2021 - September 2022

The major work is exploring the expression characteristics of plasma exosome miRNAs associated with various complications (such as hemophagocytic syndrome and mononucleosis) after EB virus infection. Through high-throughput sequencing and bioinformatics analysis, I identified 10 target miRNAs, constructed diagnostic ROC curves, and validated their clinical significance through slow virus transfection in various EB virus-infected cell lines.

Collaboration with Yueyang Hospital in KOA Research

Research Intern

January 2022 - November 2023

In this project, I invested the effects of tuina (Chinese massage) on inflammation and cytokine expression in rat skeletal muscle tissue. Utilizing a mature rat knee joint model, I induced knee arthritis through sodium iodate injection and intervened with tuina. Drawing on literature, I proposed the hypothesis that tuina might intervene in rat muscle inflammation through the PD-1/PD-L1 axis. Consequently, I established a rat knee arthritis model combined with a PD-1 inhibition group, applying tuina intervention. Post-intervention, I collected skeletal muscle tissues from the affected limb, and conducted ELISA and PCR experiments to measure cytokine and PD-1/PD-L1 gene expression, serving as indicators for muscle inflammation. Behavioral data were collected before and after the intervention to assess the progression of knee arthritis in rats.

Research in Intergrative College in SHUTCM

Research Intern and Trainee

January 2021 - Now

I recieved basic training and conducted research under the guidence of Prof. Hui Zhang in diagnostic and prognosis role the INTS family acts in HCC using bioinformatics techeques and conducted the experiments to prove. The paper which I participate as the first author was now submitted to Discover Oncology, under the peer-review stage.

Zhangjiang Brain Imaging Centre, affiliated with Fudan University

Research Assistant

June 2023 - August 2023

Assisted in maintaining daily laboratory operations, rat and mouse animal imaging (CT and MRI), and rat and mouse husbandry.

Publications

Novel plasma microRNA expression features in diagnostic use for Epstein-Barr virus-associated febrile diseases

Xu Y, Chen Y, Yang Q, Lu Y, Zhou R, Liu H, Tu Y, Shao L. Novel plasma microRNA expression features in diagnostic use for Epstein-Barr virus-associated febrile diseases. Heliyon. 2024 Feb 23;10(5):e26810. doi: 10.1016/j.heliyon.2024.e26810. PMID: 38444478; PMCID: PMC10912469.

Tuina Intervention in Sodium Monoiodoacetate Injection-Induced Rat Model of Knee Osteoarthritis

Xu Y, Zhu X, Li X, Lu Y, Wu J, Cai W, Zheng J, Wu Z, Guo G. Tuina Intervention in Sodium Monoiodoacetate Injection-Induced Rat Model of Knee Osteoarthritis. J Vis Exp. 2024 Jan 12;(203). doi: 10.3791/65770. PMID: 38284553.

Skills

  • Experiments in Vitro,

    Basic cell culture,

    Western Blot,

    PCR.

  • Experiments in Vivo

    Rats and mice bahavior tests,

    Rat fMRI in Brain.

  • Data Analysis

    Basic Bioinformatics,

    Basic Omic analysis,

    Clinical Contral Study.

  • Paper Drafting Skills

    Scientific Graphing,

    Scientific Illustration.

Languages

Language

Chinese: 

Mother Tongue

Language

English: 

Good

Education

Shanghai University of Traditional Chinese Medicine

Longhua Clinical Medicine College - Bachelor

2020 - 2025

Achievements

Oral Presentation and Abstract Inclusion in Consortium for Globalization of Chinese Medicine (CGCM2023)

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